Clicking the third party plugin, will show the exact path to the add-in/plugin files. If unchecking helps, you might want to uninstall the plugins. In MS Word for Mac > Tools > Templates and Add-ins, please verify the existence of third party add-ins or plugins. Uncheck the third party plugins to see if it helps to solve the problem. These third party add-ins might be conflicting with or disabling the EndNote CWYW add-in. In MS Word for Mac > Tools > Templates and Add-ins, please verify the existence of third party add-ins or plugins. If the above 'automation' settings are off, the Cite While You Write (CWYW) functions will not work. Then the 'preferences' will be saved correctly.

IMPORTANT: Even if the above items are on (checked), please uncheck them and close the screen and re-open the same screen once again and check the items.

make sure that both 'Microsoft Word' and 'EndNote X#' are both checked (turned on).

Go into the Apple menu (left top Apple logo).

To correctly set these options please follow the instructions below: MacOS 10.14 Mojave includes new 'Security & Privacy' functions which can prevent EndNote from being able to correctly automate. Instead nothing seems to happen or an error is thrown. When attempting to insert a citation via the Cite While You Write (CWYW) tools into MS Word for Mac under macOS 10.14 Mojave, the user is returned to the library window and the citation seems not be formatted automatically. EndNote Mac CWYW tools seem not to be working in MS Word for Mac (automation turned off)

Install endnote in word mac